Thoroughbred_Med

5+ Year Member
Jan 1, 2014
856
638
Status
  1. Pre-Medical
After a chromosomal translocation occurs, how do these new derivative chromosomes know how to line up at metaphase?

After a translocation happens to a chromosome it isn't the same anymore and so how does it know how to find its homologous partner?

My hunch is that the centromere has recognition abilities but I'm not to sure...


Can anybody help me understand this? thanks!
 

Nugester

2+ Year Member
Jul 4, 2017
750
719
Status
  1. Medical Student
You are partially correct. The homologous sequence will pair up. Any non-homologous sequence resulting from the translocation sticks out/bends and pairs with another homologous sequence. Then what the daughter cells get depends on alternate/adjacent 1/2 segregation, which leads to balanced or unbalanced gametes (viable/non-viable cells). Here is a easy picture:

Translocation Assignment Help Homework Help Online Live Biology Tutoring Help
 
  • Like
Reactions: 1 user
This thread is more than 3 years old.

Your message may be considered spam for the following reasons:

  1. Your new thread title is very short, and likely is unhelpful.
  2. Your reply is very short and likely does not add anything to the thread.
  3. Your reply is very long and likely does not add anything to the thread.
  4. It is very likely that it does not need any further discussion and thus bumping it serves no purpose.
  5. Your message is mostly quotes or spoilers.
  6. Your reply has occurred very quickly after a previous reply and likely does not add anything to the thread.
  7. This thread is locked.
About the Ads