Clinical Case

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  1. Attending Physician
I had a good OR case that I'd love to hear some thoughts on.

Case: mid 40s F booked for robotic TLH/BSO. She's super morbidly obese (BMI >70), h/o niCM but last echo shows EF ~50%. She has had recent unprovoked PEs for which she's on coumadin (w/u showed protein S deficiency) and i/s/o anticoagulation had menorrhagia requiring multiple transfusions, hence why they're operating on this lady. Other PMHx includes intermittent SVT (Holter shows recurrent ectopic atrial tachycardia ~140s, 20k beats/24h, asx), PE, htn, HL, OSA for which she's rx'd CPAP but her machine broke and hasn't been using it x 3 months+, "asthma" (no PFTs that I could tell, empiric dx from PCP, on occasional inhaled bronchodilators but no steroids). Last echo shows DCM w/ pEF (LVEDD 7.2cm, EF 55%, diffuse hypokinesis) - no valvular dz to speak of, mild LAE. Very poor views of the RV on TTE but grossly nl function, est PASP via mild TR jet ~35.

She's being admitted the night before to have an IVC filter placed preop given her high clot risk.

How would you guys approach this case? Definitely challenging to approach for me as a CA-1 but great learning. Would love to hear how others would have done it.
 
I had a good OR case that I'd love to hear some thoughts on.

Case: mid 40s F booked for robotic TLH/BSO. She's super morbidly obese (BMI >70), h/o niCM but last echo shows EF ~50%. She has had recent unprovoked PEs for which she's on coumadin (w/u showed protein S deficiency) and i/s/o anticoagulation had menorrhagia requiring multiple transfusions, hence why they're operating on this lady. Other PMHx includes intermittent SVT (Holter shows recurrent ectopic atrial tachycardia ~140s, 20k beats/24h, asx), PE, htn, HL, OSA for which she's rx'd CPAP but her machine broke and hasn't been using it x 3 months+, "asthma" (no PFTs that I could tell, empiric dx from PCP, on occasional inhaled bronchodilators but no steroids). Last echo shows DCM w/ pEF (LVEDD 7.2cm, EF 55%, diffuse hypokinesis) - no valvular dz to speak of, mild LAE. Very poor views of the RV on TTE but grossly nl function, est PASP via mild TR jet ~35.

She's being admitted the night before to have an IVC filter placed preop given her high clot risk.

How would you guys approach this case? Definitely challenging to approach for me as a CA-1 but great learning. Would love to hear how others would have done it.

GETA. Prop/roc/tube. Minimal opiates indicated, especially given her untreated OSA.

Remind the OB upfront they may have to do the case with a little less than full trendelenberg because she will be obviously difficult to ventilate. Helpful to know she doesn't have florid pHTN at least based on echo so permissive hypercapnia/mild hypoxia should be okay. Risk of converting to open is obviously much higher.

As far as ventilation, I favor a low tidal volume (6-8ml/kg IBW) and high peep (7-8) approach but play around with the vent and see how you can most effectively ventilate her with tolerable pressures. That is the fun/challenge/frustration of these cases on these patients.

Had essentially the exact same case last week but with mod pHTN. That is more challenging because it is a dangerous game letting the pCO2 climb/pO2 fall.
 
Another good rule of thumb -- if it ever crosses your mind, put an arterial line in. Given her BMI I am going to venture to guess the non-invasive cuff won't fit her arms (or legs) properly. Midway through the case you don't want to try navigating under the drapes and around the robot to try to fix it. It can also be helpful in drawing ABGs on this lady. You'll hear many experienced anesthesiologists say that they have never regretted putting an arterial line in, but have many instances where they regretted NOT putting one in.

Also, don't be in any rush to try to extubate her on the table. If the patient shows that she has any risk of failing from a respiratory standpoint postoperatively, leaving the tube in shows humility, good judgment, and prudence.
 
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Good advice from Urzuz. Also, depending on the robotic skill of the OB's involved, I may be inclined to talk them out of the robotic approach. The less time this lady spends on the table, the better for all involved.
 
Robotic surgery is going to be a terrible idea here and your attending should have a discussion with the surgeon highlighting the issues with steep trendelenburg, long surgery and all the other challenges with this FULLY developed patient.
 
I have done a case with a woman of similar "dimensions" and many of the same medical issues, except she had just moderate diastolic dysfunction due to longstanding HTN.

I agree with the others above that this is a terrible idea. In order to do this surgery they have to be in steep Tberg and this will be a challenge to ventilate her.

Another major factor here with her positioning is it places her at major risk for nerve injury. The woman I did had bilateral hand weakness due to ulnar nerve compression. It also places the brachial plexus at risk for traction injury if you use those shoulder supports on the bed. You should really discuss this risk preop with both patient and surgeon.
 
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I would refuse do do this case robotically at my institution. There's no way any good can come of 8 or 9 hours in Trendelenburg. No. Way.

We M&M'd a case just like this one a year or so ago. Morbidly obese patient spent most of the day in steep Trendelenburg. Extubated her (bad idea), lost the airway (predictable), flail ensued.

We have also had patients wake up with positioning injuries after long, long days in the robot room.
 
I thought the bugs in the robot room were worked out. In her I would want a cbc coags preinduction arterial line, if her airway looked nasty I would do an afoi. No way for a robot. This exact case I did almost 2 years ago. The surgeons brought in the robot spent all the money on the robotic set and had to go open because the trochars were not long enough. They did not even place the trochars into the body. I think the robotic set is 5-7k. Silliness..... If they want to go open from the start a low thoracic epidural may help. If not epidural due to AC maybe some intrathecal duramorph. At mine and maybe PGGS institution these patients go to the unit for the first 24 hrs. So institutional limitations may change the duramorph.
 
I thought the bugs in the robot room were worked out. In her I would want a cbc coags preinduction arterial line, if her airway looked nasty I would do an afoi. No way for a robot. This exact case I did almost 2 years ago. The surgeons brought in the robot spent all the money on the robotic set and had to go open because the trochars were not long enough. They did not even place the trochars into the body. I think the robotic set is 5-7k. Silliness..... If they want to go open from the start a low thoracic epidural may help. If not epidural due to AC maybe some intrathecal duramorph. At mine and maybe PGGS institution these patients go to the unit for the first 24 hrs. So institutional limitations may change the duramorph.
Why a preinduction art line?
 
First institutinally its very easy to place an arterial line in the preinduction room. Secondly although she has a preserved ejection I would like to monitor her blood pressure beat to beat throughout induction to quickly titrate my medications and intervene early. She does have dilated cardiomyopathy with diffuse hypokenesis I would want to ensure early on that I dont make this worsen with supply demand mismatch on induction. Thirdly we do not see much cardiac dissease in our patient population which leads my practice in being more conservative in management.
 
CA-2 Here

Beforehand, talk with OB's about large possibility that she may not tolerate Tburg for long, if at all. Even more important given her likely pulmonary hypertension. My experience is our OB/gyn's are understanding, and won't argue much if at all about not using the robot if we are saying it's best for the patient. Ideally, it's decided prior to testing ventilation after asleep. Would prefer a thoracic epidural in this patient to avoid opiates given her size.

Induction: Ramp, Prop/Succ/Tube. If her airway isn't reassuring I'd probably just start with C-MAC D-blade.
After asleep place A-line for hemodynamic monitoring given tucked arms and difficulty getting BPs and above mentioned pulmonary hypertension, mildly reduced EF.
If we are going forward with robot, test T-burg position and see if even able to ventilate. If unable to satisfactorily ventilate ---> Laparoscopic or open.
Proceed through case as usual.
End of case, on lighter side with narcotics. Depending how long case goes, if worried about airway edema, leave intubated ---> ICU. If ok, extubate awake, in reverse T. I'm ok with her being in some pain upon waking, I can slowly titrate in narcotics after she's awake and breathing.
 
I know that is right Arch!!! I am thinking the same thing.

I also agree with the other posters. No way I would let the surgeons do this lady with a robot. Laparoscopic, fine. Robot, hell no. Find another sucker. No one has mentioned the risk of blindness either with such prolong T berg positioned. And you know for sure there is gonna be good airway edema at the end of case.
 
I know that is right Arch!!! I am thinking the same thing.

I also agree with the other posters. No way I would let the surgeons do this lady with a robot. Laparoscopic, fine. Robot, hell no. Find another sucker. No one has mentioned the risk of blindness either with such prolong T berg positioned. And you know for sure there is gonna be good airway edema at the end of case.
+1
 
Bmi of 70 probably not a candidate for a low thoracic. I would still take a look and the off chance her back anatomy looks ok I would give it a shot. Likely this case will be an open incision. The surgeons are very ambitious to attempt this case robotically. This case screams huge waste of dollars by even attempting the robotic approach.
 
why did that thread on the managment company get closed? is it because he mentioned the managemetn cos name?
 
This is a challenging case, I know this because I just did it a few weeks ago. Except BMI in my pt was 68. Because I was able to get decent TV after placing the pt in max trendelenberg, we decided to proceed with the robot. The surgeon wanted to see what his views were like after insufflating and had a low threshold to go open if he felt the robotic approach would be too challenging. Luckily he was able to keep surgical time under 2.5 hrs and everything went fine. But it was getting tougher and tougher to ventilate towards the end and I don't think I could've gone another 1-2 hrs longer, despite trying every trick in the book with the vent settings. Basically this is a case that requires good communication between you and the surgeon and both of you knowing your limitations. There is no way the pt could've safely tolerated the procedure if it went on for 4+ hrs
 
BMI 70 ... OSA ... asthma ... sounds like a hypoxic disaster in the making.

I'd start with awake intubation to avoid the "cant intubate cant ventilate" possibility (which becomes more and more real as patient neck circumference exceeds average belt size).

I'll trust you guys on the during-procedure bits. Toying around with robots while she builds a lot of airway edema sounds like something to be avoided.

Post procedure, leave the tube in as long as possible. Try to send her to the ICU for recovery and let them remove the ET tube when they feel comfortable with it. (Highly likely the ICU will laugh you off, but maybe they are having a slow day and need something to keep the residents busy...) If you're stuck recovering her, take it slow. Talk to respiratory therapy and have a CPAP/BiPAP device at hand so you call pull the tube and slap a PAP mask on right away.
 
The surgeons are very ambitious to attempt this case robotically. This case screams huge waste of dollars by even attempting the robotic approach.


You know what they say about the primary difference between the men and the boys....
 
Ezekiel, I'm amazed you even made it that long. I start having difficulty with the sat and/or ventilation in robot cases once Bmi hits 50-55...even after max optimization of insp. pressure, I:e, peep etc. But yea...ramp her up, have glidescope available, prop, sux, tube. 2nd Iv and +- a-line. Be generous with the ketamine before incision and work some in when you're waking her up. Consider some decadron if case starts pushing 4-5 hrs.
 
Really appreciate all the great comments. The case (fortunately) went quite well but you guys have mentioned several things I didn't even give fair consideration when I was thinking about this case.

Had essentially the exact same case last week but with mod pHTN. That is more challenging because it is a dangerous game letting the pCO2 climb/pO2 fall.

Her pulmonary pressures were honestly one of my biggest concerns preoperatively. Even though she had a TTE with estimated PASP in the 30s, the images were quite suboptimal (not surprising given her habitus) and I was concerned that they may have underestimated the PASP based on a poor visualization of the TR jet, esp since I think that method is only decent with good images. She had severe OSA, recent PEs (and was hypercoagulable so who knows if she had reccurent PEs / CTEPH type phenomenon) and LV failure with LAE on echo. I was really worried she had significant undiagnosed pHTN and that even minimal hypoxia on induction could lead us into a bad RV failure scenario. For those of you guys that take care of sick hearts a lot I'm sure my concern was overblown but on my list of things that could send us down the tubes quickly this was high.

Robotic surgery is going to be a terrible idea here and your attending should have a discussion with the surgeon highlighting the issues with steep trendelenburg, long surgery and all the other challenges with this FULLY developed patient.

I think it's interesting that so many people have come out strongly against the robot. These cases are done (thankfully) by our gyn-onc group and they specifically do the robot for these large BMI folks (BMI>50) - apparently it's very challenging if not impossible to do straight stick laparoscopy bc you don't have enough leverage to manipulate the instruments. I don't know if that's true, but that's what I was told. They also try very hard to avoid open approach given a ~30% wound dehissance rate in patients with this BMI from open laparotomy incisions. Fortunately our surgeons are quite good at this with the robot and we were skin-to-skin in ~2.5 hours which is pretty average for our group. We definitely had a discussion preop that she would not tolerate the usual steep T-berg. After induction we tested positioning and settled on 15 degrees of t-berg which is less than they usually request for these cases but I could adequately ventilate her and they had reasonable operating conditions. Her peak pressures after insufflation were in the 45-48 range.

Another major factor here with her positioning is it places her at major risk for nerve injury. The woman I did had bilateral hand weakness due to ulnar nerve compression. It also places the brachial plexus at risk for traction injury if you use those shoulder supports on the bed. You should really discuss this risk preop with both patient and surgeon.

This is a great thought that I didn't really consider very much preop as a CA-1. We use these special "anti-slip" friction pads on the bed for these cases and even in this patient we could do 15 degrees of t-berg without her slipping and no shoulder supports/straps. Fortunately no postop neuropathy issues.


Anyway, here's how it went down. She came down with an infiltrated 20g IV from the floor (typical) and we placed a 22g for induction. We did an awake a-line and then a very stable ketamine/etomidate induction (etomidate was my choice and perhaps unnecessary but eh). Her airway actually looked pretty good, all things considered (MP1, good neck ROM albeit thick neck) and went straight to glide with no issues. RIJ TLC for access. She remained hemodynamically stable throughout. Maintenance was precedex/des/remi - a cocktail my attending (who does a lot of our bari cases) really likes but I haven't used before, not my choice. It worked well though I'm not sure what the precedex was adding on 0.6ish MAC of volatile. We tested positioning prior to any draping or whatnot and gave her 3-4 minutes supine and then 3-4 minutes in 15 deg t-berg to see how she would tolerate it. I hyperventilated her down to a etCO2 of 28-30 prior to insufflation and managed to keep her CO2 fairly well controlled during the case, though I'm sure had it gone long enough I might have run into some problems. Got her breathing and titrated in a whiff of dilaudid to keep her comfortable on emergence. SICU overnight for monitoring. She did very well and went to the floor the next day, then home on POD#4.

A few questions for you guys:

1) For access, would anyone have done this with just u/s guided peripherals given the difficulty of IV access? I've had bad luck with u/s guided IVs infiltrating in patients with this much subcu tissue, I think bc you have so little catheter in the vein - they work for a while but then crap out. Our 22g induction IV had infiltrated by the end of the case but fortunately was just running LR. Losing IVs in tucked arms on a robot on this lady sounded awful.

2) What would you have done for maintenance? The des/remi/precedex combo had a nice wakup, albeit an expensive one.

3) Would you AFOI this patient? I suggested it to my attending because of my concern re: hypoxia and her PA pressures if she turned out to be a difficult airway despite her reassuring exam. He responded that AFOI is to deal with airway issues, not hypoxia issues. Is that how you guys think about fiber optic?

I have to say a very reassuring part of this for me was she had an IVC filter placed the day before (under local) and was able to be supine for the entire ~1h placement which made me feel better about ventilating her.

Thanks again for all the feedback! This is really helpful for those of us still learning.
 
1. are you using the standard length IV's or the longer catheters?

2. I probably would have just used des for maintenance, but I like the idea of adding remi. I've never used precedex for intraop maintenence.

3. ramp and DL/glide. It really depends how the airway looks
 
The key here was good surgical team/time of 2.5 hrs. No need for AFOI unless something jumped out at you preop etc. (You have glidescope to look if you are really concerned before they go to sleep) I don't think you need a central line unless your go to spots have failed. (Can always do an EJ IV anyway) A-line is 50/50, but I would wait until she is asleep. I will repeat the nerve injury is a real problem if the case is long. It may not be the brachial plexus but the long periods of T-burg will DEF give rise to some upper extremity ailment.
 
I have to say a very reassuring part of this for me was she had an IVC filter placed the day before (under local) and was able to be supine for the entire ~1h placement which made me feel better about ventilating her.

How is this reassuring? I am not reassured......
 
U/s peripheral in a person this fat...you gotta use the 1.75" 18g or 2.00" 16g catheters. Also, it's quite useful to get flash out of plane and then switch to in plane to directly watch the catheter slide off into the vessel.
 
There's a 20gx6" brachial Aline kit that's made by arrow. It comes with micro puncture needle and a guide wire. It's my go to for USG peripheral IVs in fatties.
 
There's a 20gx6" brachial Aline kit that's made by arrow. It comes with micro puncture needle and a guide wire. It's my go to for USG peripheral IVs in fatties.

I assume by go to you mean you didn't see anything first in the a/c's that was stickable with the aforementioned longer peripheral iv's and are now being forced to do an upper arm basilic/brachial/axillary stick in someone whose arm is as big as my leg? Unless the target vessel is more than 2-2.5cm deep, getting out the arrow kit seems a bit overkill
 
Really appreciate all the great comments. The case (fortunately) went quite well but you guys have mentioned several things I didn't even give fair consideration when I was thinking about this case.

Her pulmonary pressures were honestly one of my biggest concerns preoperatively. Even though she had a TTE with estimated PASP in the 30s, the images were quite suboptimal (not surprising given her habitus) and I was concerned that they may have underestimated the PASP based on a poor visualization of the TR jet, esp since I think that method is only decent with good images. She had severe OSA, recent PEs (and was hypercoagulable so who knows if she had reccurent PEs / CTEPH type phenomenon) and LV failure with LAE on echo. I was really worried she had significant undiagnosed pHTN and that even minimal hypoxia on induction could lead us into a bad RV failure scenario. For those of you guys that take care of sick hearts a lot I'm sure my concern was overblown but on my list of things that could send us down the tubes quickly this was high.

I think it's interesting that so many people have come out strongly against the robot. These cases are done (thankfully) by our gyn-onc group and they specifically do the robot for these large BMI folks (BMI>50) - apparently it's very challenging if not impossible to do straight stick laparoscopy bc you don't have enough leverage to manipulate the instruments. I don't know if that's true, but that's what I was told. They also try very hard to avoid open approach given a ~30% wound dehissance rate in patients with this BMI from open laparotomy incisions. Fortunately our surgeons are quite good at this with the robot and we were skin-to-skin in ~2.5 hours which is pretty average for our group. We definitely had a discussion preop that she would not tolerate the usual steep T-berg. After induction we tested positioning and settled on 15 degrees of t-berg which is less than they usually request for these cases but I could adequately ventilate her and they had reasonable operating conditions. Her peak pressures after insufflation were in the 45-48 range.

This is a great thought that I didn't really consider very much preop as a CA-1. We use these special "anti-slip" friction pads on the bed for these cases and even in this patient we could do 15 degrees of t-berg without her slipping and no shoulder supports/straps. Fortunately no postop neuropathy issues.

Anyway, here's how it went down. She came down with an infiltrated 20g IV from the floor (typical) and we placed a 22g for induction. We did an awake a-line and then a very stable ketamine/etomidate induction (etomidate was my choice and perhaps unnecessary but eh). Her airway actually looked pretty good, all things considered (MP1, good neck ROM albeit thick neck) and went straight to glide with no issues. RIJ TLC for access. She remained hemodynamically stable throughout. Maintenance was precedex/des/remi - a cocktail my attending (who does a lot of our bari cases) really likes but I haven't used before, not my choice. It worked well though I'm not sure what the precedex was adding on 0.6ish MAC of volatile. We tested positioning prior to any draping or whatnot and gave her 3-4 minutes supine and then 3-4 minutes in 15 deg t-berg to see how she would tolerate it. I hyperventilated her down to a etCO2 of 28-30 prior to insufflation and managed to keep her CO2 fairly well controlled during the case, though I'm sure had it gone long enough I might have run into some problems. Got her breathing and titrated in a whiff of dilaudid to keep her comfortable on emergence. SICU overnight for monitoring. She did very well and went to the floor the next day, then home on POD#4.

A few questions for you guys:

1) For access, would anyone have done this with just u/s guided peripherals given the difficulty of IV access? I've had bad luck with u/s guided IVs infiltrating in patients with this much subcu tissue, I think bc you have so little catheter in the vein - they work for a while but then crap out. Our 22g induction IV had infiltrated by the end of the case but fortunately was just running LR. Losing IVs in tucked arms on a robot on this lady sounded awful.

2) What would you have done for maintenance? The des/remi/precedex combo had a nice wakup, albeit an expensive one.

3) Would you AFOI this patient? I suggested it to my attending because of my concern re: hypoxia and her PA pressures if she turned out to be a difficult airway despite her reassuring exam. He responded that AFOI is to deal with airway issues, not hypoxia issues. Is that how you guys think about fiber optic?

I have to say a very reassuring part of this for me was she had an IVC filter placed the day before (under local) and was able to be supine for the entire ~1h placement which made me feel better about ventilating her.

Thanks again for all the feedback! This is really helpful for those of us still learning.

What I've seen my attendings do for these big BMI cases....

1) IV access in these people is hard to begin with. If you can get a 22 gauge PIV for induction, then great. Once induced and sufficiently vasodilated, I like getting a second 18 gauge or biggger somewhere. But, you have a triple lumen with cordis... so that'll be ok. U/S is nice... but can be daunting,

2) Maintenance for an obese patient is gonna almost always be DES. Now, whether you want to use remi is completely up to you... The wake-up is nice. But, I like this trick one of my attendings taught me.
My base solution consists of 1% lidocaine (diluted down from 2%) running at 2 mg/min which is 12 ml/hr...mix in 1 mg/ml ketamine --> 12 mg/hr
And I often add 0.5 - 1.0 mcg/ml sufentanil --> 6-12 mcg/hr And the first syringe also has 2-3 g Mg SO4 in it. Run that... and turn it off. Patients usually wake up pain free and quite nicely. I also have seen them run a PIVA (50-75 mcg/kg/min propofol infusion) Cut down your volatile des... to like 0.7-08 MAC.

3) As far as airway management... if you think she's gonna be difficult.... I always go for sux and not roc. Sux has a bad rap, but it's a useful drug. The other day, I used sux on a BMI 60 patient, with severe OSA for T&A. I looked with DL... ML Grade 4. Tried glidescope, barely a ML grade 3. So we woke up him and did the intubation awake with lots of topicalization and the glide scope. Worked out well. It's just that once you're committed to Roc, you're kinda stuck...
 
Must-read article
http://bja.oxfordjournals.org/content/93/2/292.full

Mid-arm approach to basilic and cephalic vein cannulation using ultrasound guidance

This is basically what I do when other options are exhausted, but I use the 20g Arrow arterial line catheter with the built in wire. Allows you to get in at pretty much any angle, hold your position, get the wire up, and thread the catheter. That and the kink-resistant catheter is clutch.
 
I assume by go to you mean you didn't see anything first in the a/c's that was stickable with the aforementioned longer peripheral iv's and are now being forced to do an upper arm basilic/brachial/axillary stick in someone whose arm is as big as my leg? Unless the target vessel is more than 2-2.5cm deep, getting out the arrow kit seems a bit overkill

Yeah I usually go for the veins right next to the brachial artery. I can get a 2" Iv in but sometimes there's only 1/2-1cm of catheter intraluminal when it's hubbed. So I feel they are less likely to migrate and infiltrate with the 6" catheter.
 
There's a great chance that you will be unable to ventilate this patient in the position required for surgery. Your PIP's might be 60+ and plateaus 40+ once you go Tberg and insufflate.

Maybe it's worth a try, but it's also worth a preop talk that the chance of aborting and going open is relatively high. That's for you to make the Gyn understand and go over with the patient.
 
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