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Clomifene

Discussion in 'Step I' started by foofighter7, Aug 11, 2011.

  1. foofighter7

    foofighter7 Member
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    How exactly does this work to help treat infertility in PCOS?

    I don't get how it says its an estrogen agonist BUT will prevent inhibition of LH/FSH

    Thanks!
     
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  3. Ty Webb

    Ty Webb I like you Betty...
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    It's an antagonist at the hypothalamus. Therefore less estrogen binding at hypothalamus --> inc. GnRH --> inc. LH + FSH
     
  4. KillaKanye21

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    :idea:
     
  5. DoctwoB

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    Clomifene is a partial estrogen receptor agonist, which means, in the presence of estrogen at the hypothalamus, it acts as an antagonist.
     

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