Cortisol Function

[anonymousplatypus]

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In one of the TPR workbook passages, the answer explanation states that "cortisol induces gluconeogenesis and glycogen formation in the liver"

How does this work? Why would you make more glucose just to use it form glycogen when the body needs more glucose in the blood?

 

[benjaminl1nus]

I disagree with TPR here. "cortisol induces gluconeogenesis and glycogen breakdown (glycogenolysis) in the liver" is the correct answer explanation.

cortisol would induce gluconeogenesis, so as to export this glucose to the blood

and glycogen breakdown, which would also export glucose to the blood

 

[dyspareunia]

TPR is correct.

 

[benjaminl1nus]

apparently cortisol induces glycogen formation...weird. sorry for misleading you, OP, and possibly others. lol.

 

[Paean1]

Cortisol induces glycogenesis via increased glycogen synthase.

Cortisol also permits glycogenolysis via catecholamines (epinephrine and norepinephrine) and glucagon.

The main way it increases glucose is by decreasing peripheral uptake and increasing gluconeogenesis.

Why does cortisol cause glycogenesis? I have no idea. It seems counter-intuitive, but that's what the body does!

 

[anonymousplatypus]

Thanks guys! 🙂

 

[dudewheresmymd]

In one of the TPR workbook passages, the answer explanation states that "cortisol induces gluconeogenesis and glycogen formation in the liver"

How does this work? Why would you make more glucose just to use it form glycogen when the body needs more glucose in the blood?

what passage/page #?

 

[Mad Jack]

To understand why cortisol does what it does, you need to understand why it is doing it. The purpose of cortisol is to increase short and intermediate energy reserves in response to stress- an increase in blood sugar is one half of this, while glyconeogenesis is the other.

 

[dyspareunia]

To understand why cortisol does what it does, you need to understand why it is doing it. The purpose of cortisol is to increase short and intermediate energy reserves in response to stress- an increase in blood sugar is one half of this, while glyconeogenesis is the other.

Glycogenesis, not to be confused with gluconeogenesis or with glyconeogenesis. "Glyconeogenesis" is production of glycogen from non-glucose precursors. Glycogenesis (the relevant one here) is production of glycogen from glucose.

 

[SOOyC52H1Sof]

Glycogenesis, not to be confused with gluconeogenesis or with glyconeogenesis. "Glyconeogenesis" is production of glycogen from non-glucose precursors. Glycogenesis (the relevant one here) is production of glycogen from glucose.

Was it not possible to make a more clear distinction between these words?

 

[dyspareunia]

Was it not possible to make a more clear distinction between these words?

It's clear.

Glycogenesis: Creation of glycogen.
Gluconeogenesis: Creation of glucose from non-glucose particles.
Glyconeogenesis: Creation of glycogen from non-glucose particles.

You can pretty much ignore "glyconeogenesis". It's never relevant.

 

[gatorgirl23]

Cortisol stimulates gluconeogenesis during fasting state, and glycogenesis during fed state
In addition, cortisol has permissive action on norepinephrine, epinephrine, growth hormone and glucagon, which stimulate glycogenolysis

 

[JustinM88]

Epinephrine causes glycogenolysis + gluconeogenesis.

Cortisol promotes glycogenesis + gluconeogenesis

Can someone double check me here?