Cyanocobalamin and Peripheral Neuropathy

Started by Dr MD
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Dr MD

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It has been known that cyanocobalamin can be injected subcutaneously under the skin to treat peripheral neuropathy. My question though is:

Can cyanocobalamin (vitamin B12) be injected subcutaneously in the ankle to treat peripheral neuropathy in the feet? Thanks. Greatly appreciate medical neurological expertise input on this.
 
It has been known that cyanocobalamin can be injected subcutaneously under the skin to treat peripheral neuropathy. My question though is:

Can cyanocobalamin (vitamin B12) be injected subcutaneously in the ankle to treat peripheral neuropathy in the feet? Thanks. Greatly appreciate medical neurological expertise input on this.

Parenteral administration (i.e. IM or sub-cu) leads to systemic absorption/distribution of B12. To my knowledge, I have not heard of local administration of B12 providing any additional or enhanced benefit. I usually replete for B12 deficiency using 1000mcg IM daily x 1 week, then 1000mcg IM weekly x 1 month, then 1000mcg monthly. If absorption is not an issue, oral B12 can be an acceptable alternative for maintenance. The deficient patient does need to be on some form of B12 for life thereafter.

Hope this answers your question. 🙂
 
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