‎Someone from my SoM posted this in response to my school post earlier today:
"'Nowadays, a 17-alpha-alkylated anabolic androgen steroid (AAS) known as danazol is the most commonly used prophylactic drug, the exact mode of action of which has not yet been elucidated'
Pappalardo E, Zingale LC, Cicardi M (2003) Increased expression of C1-inhibitor mRNA in patients with hereditary angioedema treated with danazol. Immunol Lett 86:271276
It's pretty cool though, danazol increases C1-INH expression in PBMC despite them not having androgen receptors. I think the postulated mechanism in that paper (by no means confirmed or tested) was that it reduces the effects of oestrogen on the cells, leading to a disinhibition of C1-INH production."