10+ Year Member
- Sep 11, 2005
- Medical Student
What are board-relevant differences between these things?
quite a lot: androstenedione and DHEA are two different (but interconvertable) androgens produced in the adrenal cortex (I think the fasciculata and reticularis portions). To become an estrogen, aromatase has to be involved. Aromatase is present in granulosa cells of the ovarian follicle (I think) as well as peripherally in males and females.What are board-relevant differences between these things?
Goljan RR agrees with what wikipedia says. Estrone is the major post-menopausal estrogen because it is manufactored in the adrenal gland. When the ovaries shut down, you lose the estradiol.Can someone tell me specific differences between DHEA, testosterone, and androstenedione?
Or estrone, estridiol, estrogen, estriol?
Supposedly Estrone is the major estrogen in post-menopausal women...why?
I know there's potency differences...
Wikipedia says: Estradiol (E2) is the predominate form in nonpregnant females, estrone is produced during menopause, and estriol is the primary estrogen of pregnancy. In the body these are all produced from androgens through actions of enzymes.
well...technically...Goljan RR agrees with what wikipedia says. Estrone is the major post-menopausal estrogen because it is manufactored in the adrenal gland. When the ovaries shut down, you lose the estradiol.
I think it's probably good to know DHEA and androstenedione as 17 keto steroids, as that is what they can be referred to as in question stems.