Another resounding vote for CUNY, City College in my case. If I were starting today, here's what I'd do. To my knowledge, leaving out the
expensive new dedicated postbac program, CCNY second degree students register after the freshmen, which is no good. So I would base myself at a more obscure campus for prerequisites (maybe Lehman?) and then take upper-level sciences at City. Upper-level sciences are no problem to get into, because how many people are in a 400-level course, anyway, and there's usually no lab. There is an actual scientific community there, especially in biochem and biophysics, with talks and research opportunities and the whole deal. Can't recommend highly enough.
If you can really get some answers about "guaranteed" registration--I unfortunately don't know anyone who did this one-year program, which seems to be only in its second year--I would totally consider the year program, even though it's an extra $10K. Do they have special lecture sections for postbacs? Special labs? How do they do it?