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In general, regardless of where you attend medical school DO or MD, the material you cover during your first and second years will be pretty much the same. However, there are some differences, and this is coming for a pre-med, so take that into consideration(i.e. i don't know anything).
At any rate, from pretty much every physician i have spoken to, MDs recieve a better basic science training, so courses like biochem and pathology, are better at most MD schools. On the other hand, DO schools are known to have superior antomy courses and better clinical training during the first two years.
So, other than the stuff i just mentioned, and of course OMM, there isn't much of a difference in the pre-clinical years, but the clinical years are a differnet story. Most DO schools do not have a strong affliation with a teaching hospital, so according to the physcians i have spoken to, both MDs and DOs, the clinical training of some DO graduates can be "questionable." But is this info true? Who knows, maybe someone has a emprical study on this subject.
Actually, the two of the most well known pathology professors in the nation (golijan and friedlander) teach at DO schools. You will become very familiar with golijans material and friedlanders website(pathguy.com) when you begin to study for boards. Thats assuming that you get that far. I will agree that it seems like that there is a lot of clinical stuff during the first two years compared to what my allo buddies get. Which makes for long days.........