Does atropine have any effects on sympathetic nervous system?

[ColumbiaOrtho]

I know it is a competitive antonist for acetylcholine in parasympathetic nervous system, but is there any other mechanism that this can increase the heart rate without affecting the contractility? I was wondering if it mimics nor-epinephrine in SNS because it does not affect the contractility of cardiac muscle..

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[FeralisExtremum]

For the purposes of the DAT, no. Just think of its primary mechanism of action as taking place through competitive inhibition of the PNS. It doesn't function to activate the SNS (atropine acts as a competitive antagonist by binding to muscarinic receptors, which are not used in the SNS so it doesn't activate the SNS directly).

 

[DAT Destroyer]

I know it is a competitive antonist for acetylcholine in parasympathetic nervous system, but is there any other mechanism that this can increase the heart rate without affecting the contractility? I was wondering if it mimics nor-epinephrine in SNS because it does not affect the contractility of cardiac muscle..

This is great for the DAT

Dr. Romano


The Sympathetic and Parasympathetic Nervous Systems - Video & Lesson Transcript | Study.com