Enzyme Inhibitors TBR

[Maverick56]

What is the initial velocity of a reaction catalyzed by the enzyme ureas, if the concentration of urea in solution is .25 Km?

Can someone show me how to solve this step by step?
How do I rearrange the Michaelis Menten Equation Mathematical?
How do I get the answer?
How is Vmax related to initial velocity?

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[The Kraken]

What is the initial velocity of a reaction catalyzed by the enzyme ureas, if the concentration of urea in solution is .25 Km?

Can someone show me how to solve this step by step?
How do I rearrange the Michaelis Menten Equation Mathematical?
How do I get the answer?
How is Vmax related to initial velocity?

V= Vmax/(+Km). Follow along by writing it out on paper, much easier to visualize.

V = velocity of the reaction, can be thought of as initial velocity since the concentration of urea hasn't been used up yet, follow?

Substitute ".25Km" for all .

V=Vmax(.25Km)/(.25Km+1Km)

V=Vmax(.25Km/1.25Km)
V=(1/5)Vmax (Cancel Km's and solve (1/4)/(5/4), so one fifth.)