Step I Extrapyramidal Reactions Antipsychotics

[seminoma]

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2013 KLN says akathisia peaks at 10 weeks. FA14 has akathisia at 4 days. Kind of a big difference between the two. Anyone seen this pop up in Uworld? If so, what did Uworld say?

 

[EazyE1907]

2013 KLN says akathisia peaks at 10 weeks. FA14 has akathisia at 4 days. Kind of a big difference between the two. Anyone seen this pop up in Uworld? If so, what did Uworld say?

yeah i believe there is that exact question of akathisia on uworld but it gives the timeframe of 4 days. To my knowledge 10 weeks would fall into the category of Tardrive Dyskinesia.

 

[Transposony]

When there is a discrepancy follow FA.

 

[seminoma]

yeah i believe there is that exact question of akathisia on uworld but it gives the timeframe of 4 days. To my knowledge 10 weeks would fall into the category of Tardrive Dyskinesia.

FA says 4 months for TD. KLN says rarely within 3-6 months.

 

[thehundredthone]

There is actually an entity called tardive akathisia associated with tardive dyskinesia. But generally acute akathisia is seen within the first couple of weeks of treatment.

In the early acute form, patients occasionally develop akathisia abruptly at the onset of oral treatment, sometimes within an hour of receiving the drug (Braude et al 1983), but most patients with neuroleptic-induced akathisia have a gradual onset after several weeks of continued therapy (Ayd 1961).