Factor V Leiden and pregnancy

[neilc]

What is the standard of care when a women with Factor V Leiden wants to get pregnant? I know coumadin is out, so she has to get off that...then is it heparin injections? does it depend on hetero vs homozygous status? Just curious, as I have a sister in law that has the Dx, and I know that she and my brother are considering children. I am wondering what the latest info is, and if you have references that would be great too.

Thanks!

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[Diane L. Evans]

baby asa 81 mg daily, lmwt heparin qday.
some use 4g folic acid since co-exist with mthfr and pai-1

sho7u see high risk dr. perinatologist before conception

 

[neilc]

thanks diane! now, is that also the plan when they decide to concieve? i would assume that it is the same...but, what do i know?


thanks again!

 

[Diane L. Evans]

I would advise against BIRTH CONTROL as estrogens increase coagulopathy 40x. Folic acid prior to conception is a good idea