curious, which osteo school? you have to devise a study plan that works for you, this is super important. you have to figure out why things aren't going so well. are you just spending less time studying or are you not understanding the questions, need a good book to read for back up to the lectures, don't pay enough attention in lecture, etc. figuring out whats broken will help you in the long run. obviously the better grades you get and the better board scores you get, the better, and the better your options. that said someone matched from my osteo school with a bunch of Cs and some Bs, no As and average comlex scores, no usmle. i really think he is the exception though rather than the rule. you should also know that he did an away rotation in their anesthesia run sicu which is a notoriously hard rotation and worked hard... he is also a really likeable charismatic guy. good luck.