I need some clarification on complementation theory. this was from a passage in TBR
which of the following mutant type is incapable of complementation ?
1. Recessive mutations
2. Sex linked recessive mutations
3. Dominant mutations
4. Deletion mutations
the answer was 3. Dominant mutations. But I dont understand why having a dominant mutation would make a difference. If a mutant is recessive it will not produce the wildtype gene product but probably leave other parts of the chromosome functional. How does that differ with the dominant mutation. Ultimately its job also is to not make an essential protein product required by the cell. This should leave other regions of the chromosome functional so that complementation can take place if another mutant is involved?
I also dont understand how having deletion mutations would still allow complementation. Wouldn't the gene drastically in this case , thus making normal cell functioning implausible?
Could anyone please help me out here!!!!!!!!!!!
which of the following mutant type is incapable of complementation ?
1. Recessive mutations
2. Sex linked recessive mutations
3. Dominant mutations
4. Deletion mutations
the answer was 3. Dominant mutations. But I dont understand why having a dominant mutation would make a difference. If a mutant is recessive it will not produce the wildtype gene product but probably leave other parts of the chromosome functional. How does that differ with the dominant mutation. Ultimately its job also is to not make an essential protein product required by the cell. This should leave other regions of the chromosome functional so that complementation can take place if another mutant is involved?
I also dont understand how having deletion mutations would still allow complementation. Wouldn't the gene drastically in this case , thus making normal cell functioning implausible?
Could anyone please help me out here!!!!!!!!!!!