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If a 28 base-pair segment of double-stranded DNA contains 10 adenine residues, how many guanine residues are there?
is it 7 or 10?
28 to 14 and each has 7. Or 10 adenine 10 guanine.
I'd also like to know where this is coming from.
My take:
28 base pairs; each pair is either a A-T or a G-C
If we assume saying adenine residue is the same as saying adenine, then having 10 adenine residues, we must have 10 thymine residues, and when they pair, 10 base pairs of A-T.
28 base pairs - 10 base pairs = 18 base pairs
So there must be 18 guanine and 18 cytosine to pair up to form our remaining 18 base pairs, no?
I'd also like to know where this is coming from.
My take:
28 base pairs; each pair is either a A-T or a G-C
If we assume saying adenine residue is the same as saying adenine, then having 10 adenine residues, we must have 10 thymine residues, and when they pair, 10 base pairs of A-T.
28 base pairs - 10 base pairs = 18 base pairs
So there must be 18 guanine and 18 cytosine to pair up to form our remaining 18 base pairs, no?
Chargaff's Rule:
A + G = C + T
(I always think of it as A + G + C + T = # total number of base pairs or 1 if percentages are given)
A = 10, which means it's complementary residue, T, has 10 base pairs. Therefore, a total of 20 bases have been used between A and T, and you have 8 pairs between C and G (each with 4 base pairs).
Answer: 4 G base pairs.
You just subtracted 20 bases from 28 base-pairs (28 base pairs = 56 bases), this wouldn't turn into 8 pairs remaining.
Then you say 8 pairs between C and G, which equals 16 bases (8 of each). How does 36 bases (16 + 20) = 28 base pairs?
Finally, you answer 4 G base pairs, but the question is about the number of G bases. Also, Chargaff's rule uses bases not base pairs.