this is a question and answer from achiever test 2. Can someone explain this calculation to me?
A gene locus of two alleles belonging to a population of 10,000 members is in a state of Hardy-Weinberg equilibrium. What is the frequency of heterozygotes if 9,898 individuals collectively exhibit dominant trait?
A. 0.09
B. 0.10
C. 0.18
D. 0.90
E. 0.81
Correct Answer: C
Frequency of homozygous recessive genotype,
q2 = (10,000 - 9,898)/10,000 ≈ 0.01
Recessive allelic frequency,
q = (0.01)1/2 = 0.1
Dominant allelic frequency,
p = 1 - q = 1 - 0.1 = 0.9
From the Hardy-Weinberg equation, the frequency of heterozygotes can finally be computed as follows:
2pq = 2(0.9)(0.1) = 0.18
A gene locus of two alleles belonging to a population of 10,000 members is in a state of Hardy-Weinberg equilibrium. What is the frequency of heterozygotes if 9,898 individuals collectively exhibit dominant trait?
A. 0.09
B. 0.10
C. 0.18
D. 0.90
E. 0.81
Correct Answer: C
Frequency of homozygous recessive genotype,
q2 = (10,000 - 9,898)/10,000 ≈ 0.01
Recessive allelic frequency,
q = (0.01)1/2 = 0.1
Dominant allelic frequency,
p = 1 - q = 1 - 0.1 = 0.9
From the Hardy-Weinberg equation, the frequency of heterozygotes can finally be computed as follows:
2pq = 2(0.9)(0.1) = 0.18