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Is B-cell always activated by the T-helper cell?
Started by Deepa100
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I'm confused by this too. Books say yes, that B cells can sometimes bind to an antigen by themselves and become activated. B cells are usually stimulated by T-helper cells that release cytokines, but can also be activated by interleukins secreted by macrophages.
peer review, anyone?
peer review, anyone?
Some antigens can activate B cells without the need for T cells, but mostly the T cell is involved.
i've always thought that B cells can be activated by antigens on their own (and start clonal selection, etc) but they work MUCH MUCH better when also induced by IL-2 (?) released by Helper Ts. Please correct me if I'm wrong...
