You can get a good score with any of the decks. I really liked zanki/anking because you don't have to think at all on the cards, they are just fill in the blank, you can be half asleep with a 4 second timer set and just do the reviews. The con is that there are a lot of cards, so you will be able to do less questions, and questions are what gets you points.
With lightyear you really have to think, but atleast you know you can just watch a video then unlock the cards.
The lol deck is a must, that is really great.
USMLE Rx flashfacts is the best to really learn the material instead of just trying to hack a test. These are professionally made cards and it shows. Very good if you combine with the Duke Pathoma w/pics deck. The con is the rx algorhytm which is not as good as anki.
I used zanki/lolnotacop, because we had mandatory attendance classes 8-5 everyday so I could just mindlessly do the cards and still listen to lecture, but if I were to do it over, I would have done flash facts, lolnotacop, the pathoma deck, zanki pharm and the newest anatomy deck based off of the 100 facts pdf.
With all that being said, the deck you choose really doesn't matter at all, choose whichever one you feel you can complete the fastest so you can do more questions.