Lipitor causes diabetes?

[Rutgers2015]

Advertisement - Members don't see this ad

Okay, so more than one patient has come in saying they saw something on Tv claiming that Lipitor can cause diabetes ( apparently a doctor was saying this). Has anyone else heard of this and what's the true story on this?

Thanks 🙂

 

[DASicari]

I would think that this is probably an overreaction to the labeling changes initiated on the statin drugs on the increased risk of raising blood sugar.

http://www.medscape.com/viewarticle/759736

 

[sherlockRX]

yeah, the newest update of FDA on labels of statins, "HMG-CoA reductase inhibitors have been associated with increases in glycosylated hemoglobin and fasting plasma glucose." This is based on subgroup analyses of RCTs which observed an association between new onset diabetes and the use of an HMG CoA reductase inhibitor.

 

[npage148]

If it still improves outcomes (including those caused by diabetes) in these populations why does it matter if it increased blood sugar.

 

[PharmDstudent]

If it still improves outcomes (including those caused by diabetes) in these populations why does it matter if it increased blood sugar.

BECAUSE AN INCREASE IS AN INCREASE!!!!!!!!!! AHHHHH!!!!!
*runs around with head cut off*


🙄

 

[npage148]

You're right, I totally forgot the first rule of medicine. Treat the numbers!

 

[GreyFox2002]

I wouldn't be surprised if this was more of a "epidemiological" increase in blood sugar as opposed to something physiological occuring due to the statins. People taking statins are more likely to have other comorbidities, such as diabetes, then people not taking statins in the same age group. Also, some subsets of people seem to believe that medication alone can allow them to make poor decisions in other departments (i.e. - poor nutritional choices), which can lead to elevation in blood sugar in of itself. It'd be interesting to know if the study controlled for these kinds of factors.

 

[confettiflyer]

I wouldn't be surprised if this was more of a "epidemiological" increase in blood sugar as opposed to something physiological occuring due to the statins. People taking statins are more likely to have other comorbidities, such as diabetes, then people not taking statins in the same age group. ... It'd be interesting to know if the study controlled for these kinds of factors.

That'd be the first thing I'd control for in analyzing the data.