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Discussion in 'Internal Medicine and IM Subspecialties' started by jakstat33, May 2, 2004.
why is malaria associated with burkitt's lymphoma in endemic areas?
Malaria is a chronic infection, and that probably activates more B-cells and increases the risk of those who are susceptible (eg people co-infected with EBV who are genetically pre-disposed) to develop burkitt's lymphoma.
Like most other cancers, Burkitt's lymphoma needs initiater and promoter. Both
EBV and malarial parasite act as promoters at different stages.