Malaria and Burkitt's Lymphoma

[jakstat33]

why is malaria associated with burkitt's lymphoma in endemic areas?

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[Kalel]

Malaria is a chronic infection, and that probably activates more B-cells and increases the risk of those who are susceptible (eg people co-infected with EBV who are genetically pre-disposed) to develop burkitt's lymphoma.
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=pubmed&dopt=Abstract&list_uids=10777011
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1972671
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2998987

 

[hammersmith]

Like most other cancers, Burkitt's lymphoma needs initiater and promoter. Both
EBV and malarial parasite act as promoters at different stages.