Step II Master the Boards: Step 2 CK 3rd ed. -- ERRATA

[Delacroix22]

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I havne't seen a thread about this yet

I came across this paragraph when diagnosing Cushings:

Once the ACTH level is elevated and does not suppress with high dose dexamethasone, scan the brain with an MRI.

Essentially what this is saying is if there is no suppression with dexamethasone, it is a pituitary adenoma. I thought pituitary adenomas DO suppress when you give dexamethasone. So the book erroneously inserted the "not"... correct?

 

[rodmichael82]

I havne't seen a thread about this yet

I came across this paragraph when diagnosing Cushings:



Essentially what this is saying is if there is no suppression with dexamethasone, it is a pituitary adenoma. I thought pituitary adenomas DO suppress when you give dexamethasone. So the book erroneously inserted the "not"... correct?

Yes that's correct. if you give HIGH dose dexamethasone and it's suppressed then it's most likely ACTH from pituitary adenoma and thus you proceed with a MRI of the head.