a few good general tips came from the evoc class. some are
--drive calmly at a reasonable speed, without getting emotional in relation to the call.
--at a light intersection with two "green arrow" left-turn lanes, stay in the right-most lane--in general, you have a better view overall on the driver's side of the vehicle, and so you can better see turning traffic to the left of the vehicle.
--keep a lot of space between vehicles. i forget the exact rule, but on the interstate you will want to keep something like 50 feet behind the vehicle in front of you, even more if you can't see much in front of that vehicle. yes, people will cut in front of you, causing you to back up even further. but people will try to do that anyway when your less than ten feet behind a vehicle, which is why you should be even further back to avoid braking suddenly. people won't necessarily give you driving respect just because you're an ambulance, so drive with caution.
--"cover your brake" with your right foot (without pressing it) when you don't need to accelerate and braking potential is present (other cars, traffic lights). this cuts down your overall braking time substantially.
--in many states, drivers never yield their right-of-way to emergency vehicles, even though they can choose not to proceed with their right-of-way and let an emergency vehicle proceed. this means it can be your fault if you hit a car at an intersection without the right-of-way, no matter that you were proceeding lights and sirens! so cross intersections carefully when you don't have right-of-way, one lane at a time, being very careful to establish that the front vehicle at each lane is letting you proceed without right-of-way.
you will get used to driving these things. i was used to small cars, so what really helped me was when i made use of the fact that there is a sort of "pivot point" on the side of the rig at the rear tires (on small cars, this point is too close to the back of the car to be useful). so when you're making a turn (esp. tight ones), your rear tires will tell you the point around which the ambulance with rotate.
and yes, side mirrors are your friend, and be very careful backing up. without a spotter, you can never be sure what's behind you.