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So we know that the somatic nervous system uses acetylcholine as its neurotransmitter. We also know that all preganglionic neurons of the ANS use acetylcholine....also the postganglionic neuron of the parasympathetic. The difference is the postganglionic fibers of the sympathetic neuron. It uses N or NE (adrenergic).
The thing I see in common with somatic and parasympathetic is that they synapse close to their effector whereas sympathetic postganglionic neurons lie far away from their effector (relatively speaking).
In the grand scheme of things, does NT usage depend on the proximity to the effector? Perhaps acetylcholine has a shorter half-life than epinephrine and must be used only when synapsing close to the effector? I am beginning my neuro study for the MCAT and just thought I would ask. Thanks.
The thing I see in common with somatic and parasympathetic is that they synapse close to their effector whereas sympathetic postganglionic neurons lie far away from their effector (relatively speaking).
In the grand scheme of things, does NT usage depend on the proximity to the effector? Perhaps acetylcholine has a shorter half-life than epinephrine and must be used only when synapsing close to the effector? I am beginning my neuro study for the MCAT and just thought I would ask. Thanks.
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