Well, I think it matters who is in your class. In my PhD, program an average grade is a B or even a B+, but failing is considered lower than a B-, AND hence you need 3.0 to stay in the program (but very few people get kicked out because of grades, but they fail the qualifying or preliminary exams, which are not recorded on our transcripts). About a quarter will just leave on their own. But to be at the top, you a have to be really top. Everyone is from different countries, and the top students come from the top five universities in China AND were at the top of the class in those universities (Fudan, Nankai, Beijing, Tsinghua, Zhejiang). So, when we grade the undergraduates papers who have to take the intro to statistics class, everyone laughs about how bad the students are. Most of the TA's get a kick out of grading these papers.
It really depends on the INSITUTION where you take organic I think. An A from Johns Hopkins, UC-San Diego, or UC-Berkeley, means an A anywhere.
That is why the California state schools (UCSF and UCSD) take mostly everyone ONLY from UC-Berkeley, UCLA, and UC-San Diego and don't require PCAT. Gettin a 3.7 from those schools means a lot more than the PCAT, in my opinion.