O2 dissociation curve

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virtualmaster999

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Hey everyone!

Quick question about a part of the curve that I'm a little confused about. So, the curve shifts right when there an increase in CO2, acid, DPG, exercise, and temperature, and that means that as the curve goes right, O2 is being released easier, so less affinity. How does this come into play with metabolic rate, where an increase in metabolic rate means more O2 needed? Because wouldnt a higher metabolic rate mean the curve shifts more to the right, but that also means that O2 is being released- I thought it needs more O2 though!

Could someone clarify this for me?

Thanks in advance!
 
Hey everyone!

Quick question about a part of the curve that I'm a little confused about. So, the curve shifts right when there an increase in CO2, acid, DPG, exercise, and temperature, and that means that as the curve goes right, O2 is being released easier, so less affinity. How does this come into play with metabolic rate, where an increase in metabolic rate means more O2 needed? Because wouldnt a higher metabolic rate mean the curve shifts more to the right, but that also means that O2 is being released- I thought it needs more O2 though!

Could someone clarify this for me?

Thanks in advance!

A higher metabolic rate....such as when you are running... requires more O2 to get to the tissues. Where does this O2 come from ? Hemoglobin must release it to the body tissues so that ATP can be produced. This Hb release is shown on the curve as being shifted to the right.

Hope this helps.

Dr. Romano
 
A higher metabolic rate....such as when you are running... requires more O2 to get to the tissues. Where does this O2 come from ? Hemoglobin must release it to the body tissues so that ATP can be produced. This Hb release is shown on the curve as being shifted to the right.

Hope this helps.

Dr. Romano
Perfect and simple explanation. Thank you as always, much appreciated!
 
This helped me think about it (although it is not CORRECT it just helped me kill two birds with one stone)

For gen Chem you need to know that gasses are LESS soluble at high temperatures and so if you increase the temperature the O2 will be less soluble in hemoglobin and thus released shifting it to the right.

Again this isn't correct science but it helped me connect principles from two different subjects together if anyone else thinks that way.
 
This helped me think about it (although it is not CORRECT it just helped me kill two birds with one stone)

For gen Chem you need to know that gasses are LESS soluble at high temperatures and so if you increase the temperature the O2 will be less soluble in hemoglobin and thus released shifting it to the right.

Again this isn't correct science but it helped me connect principles from two different subjects together if anyone else thinks that way.
Nice, that's a great example too. Thanks as well!
 
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