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As you may or may not know, there were two articles this past spring in NEJM that discussed the efficacy of endovascular stroke intervention (such as intra-arterial tPA and mechanical thrombectomy). They stirred up a lot of dialogue, especially in the IR community, and recently JVIR published an article discussing the studies. You can read the opinion for yourself here:
http://www.jvir.org/article/S1051-0443(13)01050-6/fulltext
http://www.jvir.org/article/S1051-0443(13)01050-6/fulltext