Transformation zone histomorphologically shows immature squamous metaplasia with reactive/regeneretaive atypia (intraepithelial inflammatory cells are noted). P16 is performed and it is diffusely and strongly positive.
Would you go for high-grade squamous cell dysplasia based on p16 staining despite the histomorphology that supports squamous metaplasia.
Would you go for high-grade squamous cell dysplasia based on p16 staining despite the histomorphology that supports squamous metaplasia.