hi anaita
Hey Nikhil,have just sent you an email at the id you have mentioned.. nw for a question that i'm puttinfg across
Which of the following is expected to occur when T lymphocytes from apatient with chronic periodontitis are culture in vitro with dental plaque... the answer given is.. synthesis of lymphokines.., yes in the body that would be the response... but then dont the T lymphocytes require the MHC to recognise an antigen and i thought the memory cells were the B cells ??
Could you plz explain??
Periodontitis involves a 'Thymus dependent activation of B lymphocytes'. B cells recognize antigen via Ig receptors on their surface but are unable to proliferate or differentiate unless prompted by Tcell lymphokines. B cells presents antigen epitope via MHC-II to T cells, activating them to produce Interlukins which stimulates B cells to differentiate into antibody producing plasma cells.
Now to clear ur doubt- when there is periodontitis, B are activated. For T cells to be present , it had to be activated by B cells. So, when T Cells from a Chr Periodontitis pt is taken and cultured on dental plaque, the very next step that follows is lymphokine synthesis.
T cell types - Helper, cytotoxic, memory, regulatory/suppressor, natural killer T cells and gumma delta T cell.
B cells types- Plasma, memory, B1, B2, marginal zone and follicular B cells
Hope this helps.
I'm sure you'll be fine...one month is way more time than you need to review the old exams if you apply yourself. good luck!
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