Hai,

May be this would help

CALCULATIONS

1. A vial contains 3.6 ml of a 2% solution of lidocaine with 1:100,000 epinephrine. How much of each drug (mg) does the vial contain?

A 2 % solution = 2 g per 100 ml, so 1 ml of the above solution contains 0.02g or 20mg of lidocaine.

So the vial (3.6 ml) must contain 20 x 3.6 mg = 72 mg lidocaine.

A 1:100,000 soln of epinephrine contains 19 per 100L, which is 1mg per 100 ml, or O.Olmg per mL.

So the vial (3.6 ml) contains 0.01 x 3.6 = 0.036 mg epinephrine

2. The maximal recommended dose of mepivicaine is 300 mg. How many milliliters of 2% mepivicaine would have to be given to reach this level?

Once again, a 2% solution = 2 g per 100 ml, or 20 mg per mi. To reach 300 mg would require 300/20 = 15 ml

3. A new local anesthetic is available as a 0.05% solution in a vial containing 2 mi. The maximal recommended dose is 30 mg over a 4-hour period. How many vials does this represent?

A 0.05% solution = 0.05 g per 100 ml, or 0.5 mg per mi. So one vial contains 0.5 mg x 2 ml = 1 mg

To reach 30 mg, you would have to use 30 vials