Pedigree Analysis

Discussion in 'PCAT Discussions' started by EthioRx, Jun 17, 2008.

  1. EthioRx

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    Can someone enlighten me on Pedigree Analysis...
    - How to differentiate between these four..
    a) Autosomal Dominant
    b) Autosomal Recessive
    c) X-linked Dominant
    d) X-linked Recessive

    Thanks in advance....
     
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  3. ffpickle

    ffpickle Thread Killer

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    First see if it is X-linked or autosomal. If it appears only in males, it is X-linked. If it is in both males and females, then autosomal.

    I don't have a formal way of determining whether it is a recessive or dominant disorder. But suffice it to say that if it appears in every generation, we're talking about dominant. If it skips some generations, then it is probably a recessive disorder (or if there is a kid with the disease even those both his/her parents don't have it).

    DOes this make sense?
     

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