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PH vs. PI

Discussion in 'DAT Discussions' started by shal3, May 9, 2008.

  1. shal3

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    I need some clearifications plz:
    if PH< PI we'll have an overall charge of positive since we have lots of H+ and so.... we'll have a basic amino acid? how does that exactly work? I understand that a basic amino acid have an overall positive charge and an acidic one has a negative charge and that the type of amino acid can be determined from the PI but how can it be basic aa when we have lots of H+?
    would appreciate your help.

    thanks
     
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  3. doc toothache

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    Try the reverse.
     
  4. shal3

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    by "reverse" you mean acidic aa has a neg charge and basic a pos? that makes sense. but Kaplan says a basic amino acid has a pos charge. I'm still confused!!!
     
  5. doc toothache

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    Basic amino acids have an unshared pair of electrons on the nitrogen and thus have a negative charge. Acidic amino acids generate a H+ due to presence of acidic functional groups, such as -COOH.
     
  6. shal3

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  7. shal3

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    Also, if others have something to say plz go ahead.
     

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