PH vs. PI

[shal3]

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I need some clearifications plz:
if PH< PI we'll have an overall charge of positive since we have lots of H+ and so.... we'll have a basic amino acid? how does that exactly work? I understand that a basic amino acid have an overall positive charge and an acidic one has a negative charge and that the type of amino acid can be determined from the PI but how can it be basic aa when we have lots of H+?
would appreciate your help.

thanks

 

[doc toothache]

I need some clearifications plz:
if PH< PI we'll have an overall charge of positive since we have lots of H+ and so.... we'll have a basic amino acid? how does that exactly work? I understand that a basic amino acid have an overall positive charge and an acidic one has a negative charge and that the type of amino acid can be determined from the PI but how can it be basic aa when we have lots of H+?
would appreciate your help.

thanks

Try the reverse.

 

[shal3]

by "reverse" you mean acidic aa has a neg charge and basic a pos? that makes sense. but Kaplan says a basic amino acid has a pos charge. I'm still confused!!!

 

[doc toothache]

by "reverse" you mean acidic aa has a neg charge and basic a pos? that makes sense. but Kaplan says a basic amino acid has a pos charge. I'm still confused!!!

Basic amino acids have an unshared pair of electrons on the nitrogen and thus have a negative charge. Acidic amino acids generate a H+ due to presence of acidic functional groups, such as -COOH.

 

[shal3]

thanks

 

[shal3]

Also, if others have something to say plz go ahead.