This syndrome, although controversial, has a good prognosis. It is simply due to myofacial disease of the pirifimis muscle. As a result of tightness in this muscle, the structures passing beneath it are compromised including the sciatic nerve. End result will be pain in the gluteal region with often radiating pain to the extremity. It is not associated with low back pain and lacks exam finding of classic radiculopathy.
Treatment is fairly easy.
First choice will be rehab based exercise, focused on stretching the piriformis muscle. Often improves symptoms when combined with a touch of muscle relaxants, application of heat and short term NSAID's.
If the symptoms persist, intramuscular injection could be helpful. Since it is deep muscle, this should be done under fluoroscopy guidance for best result and prevention of complication like nerve damage.
In non responding cases, intramuscular injection with Botulism toxin, which is done EMG guided is the treatment of choice. This later is usually helpful.
Best people to address this is a physiatrist with interventional skills or EMG skills. Your mom will do well just find the right person to do it.
good luck