please answ these quest

[mam6701e]

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1]a defciency of which of the following enzymes would cause collagen and elatin to be defective?
A]lysyl hydroxylase
B]PROLYL HYDROXYLASE]
C]procollagen peptidase
D]lysyl oxidase

2]each of the following is a glycose amino glycan except one.which one is exception?
1]heparin
2]ceramide
3hyaluronate
4]dermaten sulphate
5]chondraten sulphate

3]leftventricular failure causes fluid retention in the body.which of the following plays a part in this increase?
a]decreased cardiac output
b]decreased secretion of renin
c]decreased secretion of aldosterone

 

[Jo23]

1]a defciency of which of the following enzymes would cause collagen and elatin to be defective?
A]lysyl hydroxylase
B]PROLYL HYDROXYLASE]
C]procollagen peptidase
D]lysyl oxidase

2]each of the following is a glycose amino glycan except one.which one is exception?
1]heparin
2]ceramide
3hyaluronate
4]dermaten sulphate
5]chondraten sulphate

3]leftventricular failure causes fluid retention in the body.which of the following plays a part in this increase?
a]decreased cardiac output
b]decreased secretion of renin
c]decreased secretion of aldosterone

1. D
2-2 ceramide
3-A

 

[mam6701e]

1. D
2-2 ceramide
3-A

thank you for your reply Jo
Could you please explain in quest # 1, why did you chose lysyl oxidase insted of prolyl hydrosilase? One of those 2 could be the answ, since lylyl hydrosilase cannot be cose we dont find it in ELASTIN (sorry I missspell it before)
Check these web please

http://www.owlnet.rice.edu/~bioe464/Lecture 24 Elastin and PG synthesis handout version.pdf

thanks

 

[Jo23]

Unfortunatelly I don't have a very good explanation. Between lysyl oxidase and prolyl hydroxilase I think the lack of the 1st one would cause more damage to both collagen and elastin because "elastin contains only a little hydroxyproline"(Lippincott's illustrated review of bichem) so I guess it needs only "a little" prolyl hydroxilase. Both of collagen and elastin definately need lysyl oxidase.
So, it's like choosing the answer that is "more" right, I guess.
Jo23

 

[mesh]

http://www.biology-online.org/dictionary/Lysyl_oxidase

 

[mam6701e]

thanks anyway guys
I apreciatte your time