Portal venous system

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Alde8127

Full Member
5+ Year Member
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I know that without the portal venous system the substances would travel to the heart and be dispersed around the body, but are there any disadvantages to this system?

Thanks :happy:
 
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Well, if the Portal venous system is blocked you can get esophageal varices. Personally, I think that'd be a terrible way to die.

A disadvantage of the working system is it processes drugs taken by mouth. The liver can inactivate quite a lot of it depending on the molecule. Some new drugs are formulated to be activated by the first liver pass.
 
Well, if the Portal venous system is blocked you can get esophageal varices. Personally, I think that'd be a terrible way to die.

A disadvantage of the working system is it processes drugs taken by mouth. The liver can inactivate quite a lot of it depending on the molecule. Some new drugs are formulated to be activated by the first liver pass.

Or you can get past that the old fashioned way and shove them up your ass.
 
There are many disadvantages to the way the human body is set up. You can see them all here:
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