This
recent survey of residency directors should be illuminating to this discussion.
It depends on the field, but overall, honors in basic sciences seem to be very low on the hierarchy of selection criteria.
This is what I'm talking about when I say it matters little in retrospect compared to other things, but at the start of MS1 those "other things" are not set in stone yet and many of them will depend heavily on the knowledge base acquired during the basic science years. I would go so far as to argue that papers like this are important for MS4s, but absolutely irrelevant for MS1s. Perhaps we could look at it this way: of everything on that list of criteria, the basic science grades are the
only item the OP will have for a few years, so relatively speaking it's the most important aspect of his ultimate application that he can control at this moment, to say nothing of how the knowledge base will impact his step scores and whatnot.
I've noticed an interesting cycle on this board over the past few years. There are always certain types of posts that pop up at certain times each year. Two that are important to highlight:
1) the "I just bombed X preclinical exam; do I still have a shot at derm/ent/ortho?"
and...
2) the "I just bombed step 1....freaking out!" thread
The responses to #1 will inevitably include advice that preclinical grades don't really matter much and to focus on step 1 which is where the money is. While there's a small, nuanced element of truth to this in some select cases, the majority of such people will unfortunately progress to #2. Contrary to prevailing sdn thought, below-average students will likely earn below-average step 1 scores. The responses to the #2 thread are much more sparse, typically saying to focus on clinicals and try to crush Step 2CK -- easier said than done.
I say this not to be morose, but to suggest that a better response to early struggles would be a full court press to figure out how to study better and maximize performance now rather than counting on acing tests and rotations that they probably will not ace without major long-term changes to their approach.