If you are going to call me out and state that my comments are not relevant, explain why they are not relevant. Afterwards, I will respond to you. Generally, if Neuronix supports a post, it contains a valid point. An undergraduate without adequate supervision that is writing an article on a field in which they are not an expert about a hypothesis that is not tested is by my definition worthless. Science is hypothesis-driven, not speculation-driven.
? You were being a jerk...my dislike of your attitude doesn't require a response. But if you are asking me to point out the flaws in your comments to the OP then okay. A "like" on your comment (regardless of who) isn't validation of its worth. At the same time i fully acknowledge a dislike (by me in this case) isn't validation of its worth either. I don't know Neuronix or you and you don't know me either. This is the interwebs...for all I know Neuronix could be one sexy gamer living in his mom's basement.
The OP has supervision...and won't get far without it.
First...the rudeness of your message to the OP was completely unnecessary. Why be so rude? What did the OP do to you?
Young students don't know what is publishable and what isn't or the effort necessary to do the job justice. Jeez...some PhDs have yet to figure this out (have you read some of the articles out there?) Being rude to the OP isn't going to enlighten them. And it's certainly not going to gain their respect/they are more likely just to ignore your comments thus making them completely unhelpful/useless.
Getting excited about your first paper or the idea of one (which is how i perceived it) and going overboard/not knowing what you're doing is on par for the course. The OP is just getting started (whether that means 1 or 2 years, most likely less) and has no idea what's up and i wouldn't expect them to. A quick pubmed search tells me there are 182 papers that employ the CRISPR/cas system, one of which was a review article that came out just this year. But the OP hasn't gotten that far, i can't be sure they even know about ncbi and pubmed. Just having an idea for a proposal to go on is quite the accomplishment for a junior in college...even if it's not all that new or exciting. Let's encourage the OP to continue developing.
What you are suggesting is worthless - writing a proposal and/or a review has great worth whether it comes to fruition or not, i don't think one needs to be particularly bright to see the worth in such an undertaking
unless you have some unique insight into a particular application (say, you are a professor who is writing a review article on your own field & then pontificating on a recent finding) - You've never written a review then...or read one? Most are not unique and as stated earlier there are too many. But it is a learning exercise whether the OP understands that or not and thus has meaning and who knows...maybe after such an undertaking the OP will gain unique insights. Having a newbie write a review is usually done in the hopes they'll learn a great deal, start coming up with ideas or expand upon ones they already have and thus improving their future works. The "expert" is there over the shoulder ensuring the necessary elements are in it.
Unless what you are suggesting is a groundbreaking idea (it's not) - you are fully aware of the OPs ideas? Should we assume your first idea for a proposal was groundbreaking? Initial proposals regardless of how genius one thinks they are are rarely if ever groundbreaking. And yet they move forward. At some point you realize how bad it was and then you're that much better on the next one/you start fixing the mediocre parts of it and it develops into something worthwhile...this is how science works/how you learn.
that no-one has considered (they have) - Again, we don't know the specifics...the review will hopefully show what hasn't been considered and revisions to the proposal can be made
and now that they considered it, they will try it (they won't), - who knows... You don't need letters behind your name to come up with something worthwhile. Steve Jobs anyone?
then this is worthless. - i hope you can figure out why it's not
Yeah, you could write something and maybe get it published in a throwaway journal. Maybe the experience will be worthwhile to you.
But what you are proposing is not respectable. - what's not respectable?
You are coming across as a graduate student with a chip on their shoulder who has recently been disillusioned by what it really means to do science. My guess..2nd or 3rd year.
This was so long i wasn't sure it was going to post...haha my apologies. Being succinct isn't my strong suit.