UCSF changed to this type of integrated curriculum a few years ago and it seems to be doing well. It's not one huge course, but several "streams" as they call it there. For example, for the biomedical stream, if the theme that week was the cardiovascular system, they would learn the anatomy, histology, biochem, microbio, and path associated with that system. This cuts down a lot on learning redundant material that students would experience if all these classes were separate. It gives the student an opportunity to learn these subjects in a greater context and also understand how they relate to one another. Learning to think this way early on will carry over well for taking boards or in clinic when you have to be able to combine the different disciplines.