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I was wondering is there any relationship between tramadol and trazodone? I know one is an analgesic and the other is an antidepressant; both have the ability to increase levels of NE and 5 HT (so Serotonin Syndrome is cautioned with concomitant use due to 5 HT increase). I think have heard once that one is a metabolite of the other but I couldn't find any information on this, so I think I misheard. Can someone please clarify?
thanks
thanks