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Emergency thoracic RT rarely helps in my experience. By then, the disease is too advanced and the patient is too decompensated. Unless a radiosensitive histology, radiation does not work overnight.
Still baller though. Any case where you are offering emergent XRT is a Hail Mary type of case. But, to get it done immediately and very quickly, without utilizing a lot of resources (and a bit creatively) lets the team move on to the other options or breach the hospice discussion earlier.Does it matter…did emergent RT help? Fortunately, I’m 100% outpatient based so I don’t have to make these decisions.
On the other end of the spectrum you havent really lived until you get paid to randomly fill out a survey about which third line fake believe immunotherapy would be best.FTR have seen ICU cases benefit tremendously from Emergent RT.
One case got out of ICU and had about 2 weeks of quality at home. Two weeks may seem like little but he would have died in the ICU otherwise.
The other (remarkably) had a full year before progression.
Far from the norm, but I've given up my crystal ball and try not be nihilistic. I've seen enough patients in follow up where their initial de Novo presentation would make me think "this patient's a goner" and aggressive upfront treatment managed induce remission that I feel rolling the dice is warranted.
Of course, different from 3rd line therapy with terrible performance status prior to their immediate hospitalization...
Ok how this? Icu pt on vent. Imported the diagnostic scan into eclipse and drew the field and then brought pt down and used a cone beam/kv to center on carina and give 8 gy off cord without a sim in under 2 hrs total
Does it matter…did emergent RT help? Fortunately, I’m 100% outpatient based so I don’t have to make these decisions.
I will never forget. Residency around 2002. I had just read about a randomized trial where palliative RT for lung cancer was given in a 17 Gy/2 fx schedule. It wowed me. We had a lady on vent knocking on deaths door and were consulted for palliative RT for huge lung mass. I begged attendings to try the dangerous, horrifying, risky 8.5 Gy per fraction treatment. The lady was almost dead so I guess that’s why they relented. Treatment delivered without difficulty.![]()
Used to feel great, doing commando heroic inpt RT on ICU patients.
Now that I'm in a freestanding, can't treat anyone with more than a nasal cannula and honestly i think that's probably for the better based on what I've seen with those really sick pts getting RT, end of life
My hospital hates treating impatiens and I have had endless meetings over the yrs abt this. Once I gave 8.5 gy x 2 to a homeless additct on a vent and he left the hospital 2 weeks later. Guy would have been on a vent for at least 2 months before he died w/out xrt (no distant disease). I made a real effort to calculate savings, but they don’t really care. They just look at the bill and think they would have recovered it as an outpt.I will never forget. Residency around 2002. I had just read about a randomized trial where palliative RT for lung cancer was given in a 17 Gy/2 fx schedule. It wowed me. We had a lady on vent knocking on deaths door and were consulted for palliative RT for huge lung mass. I begged attendings to try the dangerous, horrifying, risky 8.5 Gy per fraction treatment. The lady was almost dead so I guess that’s why they relented. Treatment delivered without difficulty.
One month later the ICU lady comes walking in department… “They told me I need to come in for more lung radiation.” Rescans looked wonderful, lots of response. Everyone gobsmacked; attendings a little angry trying to decide how much more lung radiation she would need.
We all have stories!
What am I missing here? The SF arm isn't even using SF for early glottic cancer.Another day.. another academic effort to reduce fractions.
OH well... Off to work we go
Yep, AF arm is roughly what most of us have been doing for years anyway for early stage glottic CA. (This goes back at least 12-15 years.)What am I missing here? The SF arm isn't even using SF for early glottic cancer.
Yep, AF arm is roughly what most of us have been doing for years anyway for early stage glottic CA. (This goes back at least 12-15 years.)
The inexorable trend to eliminate as much radiation oncology as possible. Even if it is just one fraction at at time.What am I missing here?
There's a whole branch of 'research' being done in this space from WashU.... didn't know it was even necessary to document the times I've done this lolOk how this? Icu pt on vent. Imported the diagnostic scan into eclipse and drew the field and then brought pt down and used a cone beam/kv to center on carina and give 8 gy off cord without a sim in under 2 hrs total
Another Japanese trial in my inbox --- 54 Gy/15 fx prostate. FUP 77 months. No G2 GI or G3 GU long term sxs noted.
APM has re-entered the building, but wearing a clown outfit and called something else
Yes, time to bury it.
Next candidates:
FLASH
PULSAR
…
“Pulsar?”
Wut
Yes, time to bury it.
Next candidates:
FLASH
PULSAR
…
CHART improved survival in NSCLC, the only RT dose trial in Stage III ever proven to do soView attachment 374105
Behold, I made a meme!
And since PULSAR or FLASH alone are too simple, I would like to introduce to you the concent of PULSAR-FLASH!
1 second of RT every 6 weeks for your Stage III NSCLC! Works like a charm!
(and rad oncs have to work on the weekend)
Cancer cells do not undergo mitosis during the weekend. I tell that to all my patients.If there is no evidence to suggest working on the weekend makes a difference then...
If they don't consume any sugar over the weekend, sure.Cancer cells do not undergo mitosis during the weekend. I tell that to all my patients.
They need to get that publication out ASAPWas always skeptical of abscopal and partial metastatic ablation, particularly in unselected, asymptomatic patients.
Identifying and treating high risk, asymptomatic bone metastases is still promising.
Radiation therapy for high-risk, asymptomatic bone metastases may prevent pain and prolong life - American Society for Radiation Oncology (ASTRO) - American Society for Radiation Oncology (ASTRO)
Phase II trial suggests radiation could ward off complications of bone lesions and extend overall survival for patients with advanced cancerswww.astro.org
Does alcohol count?If they don't consume any sugar over the weekend, sure.
Just the "sugars" on the nutritional readout. Cancer runs on fructose and nothing else is my understanding.Does alcohol count?
Nothing some vitamin C infusions can't addressJust the "sugars" on the nutritional readout. Cancer runs on fructose and nothing else is my understanding.
I never want to be a proven shill for ASTRO.protons for breast full steam ahead....
Can we please not have the enemies of 95%+ of Rad Onc (people who shill protons for all diagnoses regardless of appropriateness) leading the organization, please?Good for Chuck!
He is one of the nicest guys in our field that I have interacted with. He has tons of commitments and volunteers with a bunch of organizations like the Radiosurgery Society, but he recently took the time to give me a really detailed reply to a question I've been working on. Not the usual one liner or crickets that I get when I email a dept chair.
We could do a lot worse for the leadership of ASTRO.
I think some of the people from upenn and maryland would disagree that “he is the nicest guy” he is driven.Radiation been putting food on the table of the Simone family tree for decades now.
I have trouble trusting those who button their entire white coat.I think some of the people from upenn and maryland would disagree that “he is the nicest guy” he is driven.
I have trouble trusting those who button their entire white coat.
bow tie is worse.
In europe rad oncs wear shorts and sandals. Seen it.
“Professionalism”
Drunk chairmen, Handsy chairmen, benzo dependent chairmen, outwardly racist chairmen? No problem. They are leadership, so by definition, whatever they do is professional.
Resident doesn’t wear a tie during RadBio week / clinic - called “Unprofessional” by chair
Resident doesn’t clean shave - called “jihadi” by chair.
Resident asks if NP can see the 6th inpatient of the day - unprofessional
Junior faculty experiencing post partum depressing needing an extra month? Unprofessional since the team will have to pick up her slack
Ahh, I love professionalism. When I’m a big shot, I’ll get to use that weapon, too!
i don't know if i trust or really care about what UPENN or Marylands folks thinkI think some of the people from upenn and maryland would disagree that “he is the nicest guy” he is driven.
WASHU circa just before 2000 has entered the chat.. And kicked all your asses.. Everyone is crying and the black female resident has been manhandled by a small racist man from Kentucky..Unfortunately academic leadership is like politics. It only attracts people with significant pathologic personality issues, and these are the people who make the decisions that affect the rest of us just trying to do our work and have normal lives.
Stanley order at HopkinsWASHU circa just before 2000 has entered the chat.. And kicked all your asses.. Everyone is crying and the black female resident has been manhandled by a small racist man from Kentucky..
“Professionalism”
Drunk chairmen, Handsy chairmen, benzo dependent chairmen, outwardly racist chairmen? No problem. They are leadership, so by definition, whatever they do is professional.
Resident doesn’t wear a tie during RadBio week / clinic - called “Unprofessional” by chair
Resident doesn’t clean shave - called “jihadi” by chair.
Resident asks if NP can see the 6th inpatient of the day - unprofessional
Junior faculty experiencing post partum depressing needing an extra month? Unprofessional since the team will have to pick up her slack
Ahh, I love professionalism. When I’m a big shot, I’ll get to use that weapon, too!