Previous applicants I have known or have been in contact with received their graduate degrees from some top schools. One with a Ph.D. from UC Berkeley in Biophysics got into U Michigan, one with a Ph.D. from Wayne State got into Wayne State, five with Ph.D. from Johns Hopkins Medical, and 2 of them got into Johns Hopkins Med, one got into Einstein and two got into U Maryland and Boston U, and one with Ph.D. from Duke got into Duke. This trend seemed to recur... I think the reputation matters somewhat... But again those people didn't get straight "A" in their graduate courses either, those top schools tend to give a whole bunch of B and B- in their Ph.D. required courses since it is the schools' goal to encourage research but not straight A. Students are told simply "pass" the courses so that they may carry on with research, and that is the reason those top grad school tried to deflat grades to discourage too much time spent on study. So when the top Ph.D. dudes apply for med school, they better have publications to back themselves up. But with a less known grad school, such problem may not occur, which should give you a better GPA.