review source errors

[Pox in a box]

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Anyone else find it extremely frustrating when a review source blatantly misses the mark when it comes to their terminology? For instance, can anyone tell me the difference between hypertrophy and hyperplasia?

What does BPH stand for and does it matter if it's hypertrophy or hyperplasia? Perhaps this should be a "Pimp each other" addition but it seems worthy enough for a little rant.

 

[Row Jimmy]

Anyone else find it extremely frustrating when a review source blatantly misses the mark when it comes to their terminology? For instance, can anyone tell me the difference between hypertrophy and hyperplasia?

What does BPH stand for and does it matter if it's hypertrophy or hyperplasia? Perhaps this should be a "Pimp each other" addition but it seems worthy enough for a little rant.

I remember looking this up on eMedicine during Gen Path and even the different authors use both terms for BPH (hyperplasia and hypertrophy) but they all stated it was a proliferation of cells = hyperplasia.

Is it important? I don't know but I do know that I have done a lot of questions asking about endometrial hyperplasia and hypertrophy and breast hyperplasia during pregancy. I also recall something about BPH causing bladder hypertrophy. Then, what happens to the remaning kidney if a persons donates the other? Stuff like that.

RJ

 

[Pox in a box]

I remember looking this up on eMedicine during Gen Path and even the different authors use both terms for BPH (hyperplasia and hypertrophy) but they all stated it was a proliferation of cells = hyperplasia.

Is it important? I don't know but I do know that I have done a lot of questions asking about endometrial hyperplasia and hypertrophy and breast hyperplasia during pregancy. I also recall something about BPH causing bladder hypertrophy. Then, what happens to the remaning kidney if a persons donates the other? Stuff like that.

RJ

YEAH, it's important. Ask anyone with BPH if it should matter.

 

[Janders]

For instance, can anyone tell me the difference between hypertrophy and hyperplasia?

Hypertrophy-- Increased size of cells. If you go lift heavy weights at the gym, and after a few months your muscles get bigger, this is the main mechanism. The individual cells each grew larger, no new cells are formed*.

Hyperplasia-- Increased number of cells. Actually new cells! Still can result in a bigger organ or tissue, but through a different mechanism. An example is Congenital Adrenal Hyperplasia.

As for BPH, its just a messed up term. You can say hypertrophy or hyperplasia. The way it was explained to me is that the cellular mechanism is hyperplasia, ie there are more prostate cells. But looking at it on the organ-only level, you could say the prostate hypertrophied. Silly, I know. But you know traditions.

Anyway, this site has the same explanation as above.

*in resistance-exercise-induced-muscle-growth, there is a minor amount of hyperplasia. But hypertrophy is by far the main mechanism of growth in normal individuals.

 

[streetdoc]

BPH is hyperplasia. i remember goljen going on and on about that as well as our path faculty at school. if it is due to increase in hormone, it is hyperplasia (in bph it's increase in estrogen and dihydrotestosterone due to some (i forget) reason). however, if you go to the clinics you hear it called both. i fell i'll have to side with the phDs on this one. is it important? no clue...
streetdoc

 

[HiddenTruth]

BPH is hyperplasia. i remember goljen going on and on about that as well as our path faculty at school. if it is due to increase in hormone, it is hyperplasia (in bph it's increase in estrogen and dihydrotestosterone due to some (i forget) reason). however, if you go to the clinics you hear it called both. i fell i'll have to side with the phDs on this one. is it important? no clue...
streetdoc

i think as a general rule, if it's endocrine related, then it is hyperplasia (there may be exceptions to this also). Also, i have seen both thyroid hypertrophy and hyperplasia, i don't get it either. And tissue behind blockage usually is compression atrophy (hydropnephrosis, pancr duct in CF). Compensatory responses (removing one kidney, HTN) should be hypertrophy.

 

[streetdoc]

i think as a general rule, if it's endocrine related, then it is hyperplasia (there may be exceptions to this also). Also, i have seen both thyroid hypertrophy and hyperplasia, i don't get it either. And tissue behind blockage usually is compression atrophy (hydropnephrosis, pancr duct in CF). Compensatory responses (removing one kidney, HTN) should be hypertrophy.

someone has been listening to their Goljan...
i believe those were his words exactly.

streetdoc

 

[HiddenTruth]

someone has been listening to their Goljan...
i believe those were his words exactly.

streetdoc

😀

 

[carrigallen]

1. Benign Prostatic Hyperplasia = correct terminology, used by modern pathologists

2. Benign Prostatic Hypertrophy = old-fashioned term, antiquated

The prostatic cells are hyperplastic. No modern textbook will call it "benign prostatic hypertrophy", unless they are old review books.

 

[DOCTORSAIB]

This BRS path mistake cost me a point on my path exam...

Remember, Polyarteritis Nodosum is NOT associated with P-ANCA. BRS path says it is, and its even bolded. So under the Vascular Dz chapter, under Vasculides, under Polyarteritis Nodosum, cross-off P-ANCA.

According to our path prof, P-ANCA is often associated with microsopic polyangitis and Churg-Strauss vaculitis.

Hope that helps. Good luck studying for boards!