Interesting how varied the responses are for a fairly algorithmic aspect of our profession. I would think there would be little variability among ED docs for RSI.
If one does a search for "rocuronium before etomidate" or "scott weingart rocuronium before etomidate" or variations of that query, one will find several articles and discussions about the benefits. It appears the benefit is most pronounced for those with severe hypoxic respiratory failure.
Here is the reason why I originated this thread:
I responded to a code blue on the floor. Pt had a pulse, breathing, and was markedly obtunded. She had a draining chest tube out of the right hemithorax for a malignant pleural effusion. HR 120, BP 110/75, RR ~24, SpO2 100% via 100% NRB. She would open her eyes to noxious stimuli and not show me "two fingers". I had a very poor and disappointing interaction with an ICU nurse who floats around and responds to floor code blues. First I mentioned "why is this a code blue, pt isn't undergoing CPR" and she quips (paraphrasing) "code blues are not only for cardiac arrest but also for respiratory arrest for patients who need to be intubated, according to ACLS guidelines. Why is this something that I constantly have to teach or tell people about." Obviously this rubbed me the wrong way, whether she is right or wrong, as that is not the way to speak to someone at all regardless of position or rank, let alone someone who outranks her. Anyway...I grumbled a little bit and stayed. Pt did "need" to be intubated whether it was that minute or 5-20 minutes from now. For instance, if she were an undifferentiated patient who rolled into the ER like this, I would probably have done some investigative work for the next 10-15 minutes or so while being in the room to determine why she was so obtunded. You know general stuff like physical exam (can she protect her airway, stick a qtip in the back of her nose doses she wince), FSG, EKG, CXR, getting history, do I need to activate stroke, etc. So I stayed. Mind you intubating patients in floor rooms is the worst place to do it, the beds suck, there is no room to do anything, there are 10-15 people in the room, it's chaos despite all our training that we should be calm, etc.
So pt looked to be <= 60 kg, so I had nurses draw up etomidate 10 mg IV, rocuronium 100 mg IV. We set up to tube and I tell the same nurse please push roc then etomidate, one immediately after another. Now...picture this. There are at least10 people in the room, and another 5-8 leering eyes just outside the room. There is low level pitter-patter but I'm the only one talking at a normal voice. The nurse then said, in a voice louder than mine..."WHAT, you want me to push a paralytic before a sedative? I HAVE NEVER SEEN THIS BEFORE. THIS NEVER OCCURS UP IN THE ICU AND IN THE ER WHEN I'M IN THE ER. This is a terrible thing to do. I OBJECT TO DOING THIS!" I did briefly explain that due to the pharmacokinetics of the drugs, there is less apneic time, and in this case it probably doesn't even matter, but she wasn't listening. I looked around the room and there were other nurses and the hospitalist who all had eyes like 👀 and
while looking at me.
I almost asked the nurse to leave the room right at that time I was so mad at her.
We proceeded with an uneventful tube and I left the room never acknowledging that nurse again. I asked one of the RT's afterwards what her name was, and he said "oh her? yea we all have problems with her." I go back to the ER fuming inside, wondering if I should write her up. I have never written anybody up. I talked to one of my fellow ER docs and she also has had problems with that RT.
About 2-3 hours later the nurse came to the ER to apologize to me. I asked her to talk to me in the supply room where nobody else was around. I don't remember her exact words, but she did give some bull**** apology like "I'm sorry BUT...." and really didn't issue a general heart felt apology. She was focused mostly on the notion I said it shouldn't be a code blue to begin with, and I responded by saying ultimately I stayed, the patient was tubed, and it was a good outcome. I left the room as she was trying to talk to me more. I was so pissed at her. With respect to timing of the paralytics and sedatives, I told her she can go talk to the attendings at Cornell where I learned this in residency.
I've decided not to write her up, but if I ever see her again in a room with a patient I'm taking care of I will ask her to leave.