Are you interested in MD or DO programs? If your slogan under your screen name is accurate and you're shooting for DO programs, I wouldn't stress the calculus too much. But, on the other hand, if you're shooting for MD programs, nearly one third of them currently require calculus. By the time you're ready to apply, that number will surely increase as programs become more competitive. If you are thinking about MD programs, I would probably take calculus (this coming from someone who HATES math!!!!) I'm not sure how adcoms would feel about a C from a community college and I'm sure that you could do much better now at this time in your life. I read your post in the non-trads forum about wanting to finish up your pre-reqs and take the MCAT next Aug, and as a fellow 26yo female, I can understand the need to "future plan", but I think that preparation for medical school isn't really something to be rushed. With the proper support system, things will all fall into place. Let me know what you still need to take as far as pre-reqs, so I have a better idea of your timeframe. If you do decide to skip calculus, of the other choices you gave, I would choose micro (but then again, I'm a total micro geek). Hope this helps!!