Smooth muscle contraction

[viper]

Page 343 of FA - it shows that when myosin is phosphorylated there is relaxation. BRS cell bio says it should contract. I have heard people argue that the FA is correct and argue that it is incorrect - which is it????


Thanks,

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[HiddenTruth]

Page 343 of FA - it shows that when myosin is phosphorylated there is relaxation. BRS cell bio says it should contract. I have heard people argue that the FA is correct and argue that it is incorrect - which is it????


Thanks,

woah that's wrong. I have always learned that phosph MLCK is active, and can then phosph myoslin to brind with actin--> contr. In fact, to give you a better ex. look at NO--it activates guanylate cyclase-->cGMP-->activating protein kinase G-->activates PHOSPHATASE, which dephosph MLCK, leading to relaxation.