moto_za

Member
10+ Year Member
Jan 16, 2006
1,581
44
261
Status
Can someone please help me with the following question. I thought it said in the passage that Ca helps with clot formation and not preventing it??

13. Which of the following compounds, when added
stored whole blood, BEST prevents clotting?
 

eikenhein

Supreme Commander Anesthesiologist
Lifetime Donor
10+ Year Member
Apr 9, 2006
1,671
537
281
Status
Attending Physician
Can someone please help me with the following question. I thought it said in the passage that Ca helps with clot formation and not preventing it??

13. Which of the following compounds, when added
stored whole blood, BEST prevents clotting?
Calcium chelating substances like citrate are added in vials to prevent the blood from clotting.
 
May 23, 2014
97
18
11
Status
Pre-Medical
"y-carboxyglutamate is an excellent chelator of Ca2+ and, following injury, acts as an anchoring mechanism between calcium-dependent coagulation factors and the phospholipid membranes of platelets. The functional significance of this event is that it brings specific factors together that aid in the formation of a clot, thereby accelerating clot formation many fold."

I'm confused like the original poster. This is the excerpt from the passage that makes it seem like the y-carboxyglutamate accelerates clot formation rather than prevents it.