UWorld Question 2104

[tco]

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MHC II on T-helper cells? What did I miss? Am I just really tired/hungry right now?

 

[iA-MD2013]

I saw that too...and I don't believe it!

 

[tco]

I saw that too...and I don't believe it!

I based my answer on the fact that the cells had MHC II...I said, "It can't be T cells." I guess I'll send them some feedback.

 

[iA-MD2013]

I based my answer on the fact that the cells had MHC II...I said, "It can't be T cells." I guess I'll send them some feedback.

how exactly did they word it? I remember thinking that they were referring to the TCR.

 

[iA-MD2013]

they say the cell expresses "MHC class II antigen." that sounds more like the T cell receptor (the antigen) that binds MHC II?
or maybe it really is a mistake...there's no way T cells express MHC II.

 

[Step1Hash]

they say the cell expresses "MHC class II antigen." that sounds more like the T cell receptor (the antigen) that binds MHC II?
or maybe it really is a mistake...there's no way T cells express MHC II.

isn't the 'MHC II antigen' what the MHC II is presenting? I think it's a mistake also.

 

[tco]

how exactly did they word it? I remember thinking that they were referring to the TCR.

I don't know what all I'm allowed to post.

Basically, it's a question asking about acute rejection and it says the cells involved are "abundant mononuclear cells expressing MHC class II and IL-2 receptors."

In the answer explanation, it says that the "mononuclear cells expressing MHC class II antigen and IL-2 receptors are CD4+ (T-helper) lymphocytes."

 

[Celestine]

I don't know what all I'm allowed to post.

Basically, it's a question asking about acute rejection and it says the cells involved are "abundant mononuclear cells expressing MHC class II and IL-2 receptors."

In the answer explanation, it says that the "mononuclear cells expressing MHC class II antigen and IL-2 receptors are CD4+ (T-helper) lymphocytes."

I think "receptors" is referring to both receptors for MHC class II and IL-2. They probably should have written it twice. Bah.