Nothing is more unfavorable than Iraq and Afghanistan so I'm fine with working wherever anyone has a store. I'd prefer to work in an inpatient or ambulatory care pharmacy in a clinical capacity since interventions-tracking is one of my favorite things to do as a volunteer but when it comes down to brass tacks, if I need to work in retail for X years in order to get enough experience / wait for a position to open in a hospital, so be it.
Your willingness to be "semper gumbi" (Forever flexible)will put you head and shoulders above people who are either tied to one area because of family or other reasons and who are just afraid of change.
What about a residency? Clinical pharmacists that give talks at my school say that one year of residency is about 3-5 years of experience. Some of them say that they would not have gotten their clinical positions two years after graduating from pharmacy school if they had not done the residencies. They said they would probably have to work 6-10 years after being licensed to even be able to apply for the clinical positions. So in that way, they saved 4-8 years and went straight to the clinical position.