Wernicke Encephalopathy symptom timecourse

[EarlyCareerAcademicPsych]

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Very specific question:
— can the ophthalmoplegia in Wernicke’s encephalopathy wax and wane?
— how quickly does the pathology manifest in response to glucose load (whether by IV or by PO)?

References to support clinical experience would be highly appreciated.

Thanks in advance

 

[deathmerchant]

Very specific question:
— can the ophthalmoplegia in Wernicke’s encephalopathy wax and wane?
— how quickly does the pathology manifest in response to glucose load (whether by IV or by PO)?

References to support clinical experience would be highly appreciated.

Thanks in advance

I am too lazy to do a Lit search, so you are gonna have to look these up on pubmed.
What I think-

-Yes ophthalmoplegia can wax and wane. Especially in early stages. May be when the pathology is not complete. Also the Cortex has the ability to transiently correct eye movt abnormalities.

- Probably depends on how much reserve someone has. I would think probably few hours to a couple of days.

Let us know if you find anything different!

 

[EarlyCareerAcademicPsych]

Ok, will do